Peer-reviewed veterinary case report
Olfactory neuroblastoma in a horse.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2006
- Authors:
- Yamate, Jyoji et al.
- Affiliation:
- Department of Veterinary Pathology · Japan
- Species:
- horse
Plain-English summary
An 11-year-old thoroughbred gelding had to be put to sleep because he had a tumor in his right nasal cavity. The tumor was made up of unusual cells that showed signs of being related to nerve tissue. This type of tumor, called olfactory neuroblastoma, is rare and can look different under a microscope. Unfortunately, the horse's condition was serious, leading to the decision for euthanasia.
Abstract
An 11-year-old thoroughbred gelding was euthanatized because of right nasal cavity tumor. The tumor consisted of round to oval cells with a scanty cytoplasm and hyperchromatic nuclei. Homer-Wright rosettes and pseudorosettes, as well as microcysts were seen. Neoplastic cells were immunoreactive to vimentin, S-100 protein, and neuron-specific enolase, glial fibrillary acidic protein and microtube-associated protein in varying degrees, indicating neurogenic nature. Based on these findings, this tumor was diagnosed as an olfactory neuroblastoma. Since this type is an uncommon tumor showing histological variety, the nature is discussed.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16757894/