Peer-reviewed veterinary case report
Multiple Sex Cord-stromal Tumors in a Standardbred Stallion Testis.
- Journal:
- Journal of equine veterinary science
- Year:
- 2023
- Authors:
- Roxon, Caroline et al.
- Affiliation:
- Department of Clinical Studies (Roxon · United States
- Species:
- horse
Plain-English summary
A 12-year-old Standardbred stallion had a growing mass in his left testicle for the past five months, along with a noticeable decrease in size of that testicle. A veterinary examination using ultrasound showed a firm mass in the left testicle, measuring about 2.5 by 2.3 by 1.9 centimeters, along with two smaller areas that looked abnormal. Because there was concern that these findings could indicate a more serious type of tumor, the veterinarians decided to remove the affected testicle. After surgery, they found multiple masses and determined that the larger one was a Sertoli cell tumor, while the smaller ones were mixed tumors containing both Sertoli and Leydig cell types. This case is notable because it is the first time such tumors have been reported together in a single testicle of a horse.
Abstract
A 12-year-old Standardbred stallion presented with a 5-month history of a growing mass in the left testis as well as an overall decrease in left testicular size. Palpation and ultrasonography of the left testis revealed a firm, hypoechoic, clearly delineated soft tissue mass in the craniolateral portion of the testis that measured 2.5 × 2.3 × 1.9 cm. Two smaller, hypoechoic regions also were visible ultrasonographically in the left testis, suggesting the presence of multifocal/multicentric neoplasia. The affected testis was very small (testicular volume of 40.3 cm). The right testis was significantly larger (144.3 cm), and the parenchyma was ultrasonographically normal. Due to the concern that these findings could indicate the presence of a more aggressive tumor type, unilateral orchiectomy was performed. Multiple soft tissue masses were identified grossly, and histopathologic evaluation identified the larger mass as a Sertoli cell tumor and the two smaller masses as mixed sex cord-stromal tumors with Sertoli cell and Leydig cell differentiation. To our knowledge, this the first report of concurrent Sertoli cell and mixed sex cord-stromal tumors in a single descended equine testis.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/36775076/