Peer-reviewed veterinary case report
Malignant Glomus Tumour (Glomangiosarcoma) with Additional Neuroendocrine Differentiation in a Horse.
- Journal:
- Journal of comparative pathology
- Year:
- 2016
- Authors:
- Peters, M et al.
- Affiliation:
- Chemisches und Veterinä · Germany
- Species:
- horse
Plain-English summary
A 13-year-old Icelandic crossbred horse was having trouble chewing and was shaking its head. A lump was found in the front part of its upper jaw, which was causing damage to the bone and teeth in that area, along with growths in the nasal passages. Unfortunately, the horse did not get better with chemotherapy, and the decision was made to humanely put it to sleep. The lump was identified as a type of cancer called a malignant glomus tumor, which is unusual in animals. Sadly, the treatment did not work, leading to the horse's passing.
Abstract
A 13-year-old Icelandic crossbred horse was presented with headshaking and progressive impairment of chewing. A slowly growing mass was identified in the anterior maxilla. This was associated with lysis of the alveolar bone and the roots of the incisors and there were nodular proliferations affecting the nasal septum and conchae. There was no response to chemotherapy and so the horse was humanely destroyed. Based on morphological, immunohistochemical and ultrastructural findings the mass was classified as a malignant glomus tumour with multifocal vascular spaces and additional neuroendocrine differentiation. An oronasal glomus tumour with neuroendocrine differentiation has not been described previously in an animal.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27102445/