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Peer-reviewed veterinary case report

Insulin resistance in cats.

Journal:
The Veterinary clinics of North America. Small animal practice
Year:
2010
Authors:
Scott-Moncrieff, J Catharine
Affiliation:
Department of Veterinary Clinical Sciences · United States
Species:
cat

Plain-English summary

Insulin resistance in cats means that their bodies don't respond well to insulin, which is important for managing blood sugar levels. This condition is often seen in cats with type 2 diabetes, and if it can be resolved along with good control of blood sugar, it might lead to a remission of the diabetes. For cats that need insulin, this resistance can show up as not getting better even when they receive the right amount of insulin. The article discusses the challenges of insulin resistance in these diabetic cats.

Abstract

Insulin resistance is defined as decreased sensitivity to insulin. Insulin resistance is an important component of the pathogenesis of type 2 diabetes mellitus (DM), and resolution of peripheral insulin resistance in cats with type 2 DM together with good glycemic control may result in diabetic remission. In insulin-dependent diabetic cats, insulin resistance is manifested clinically as an inadequate response to an appropriate pharmacologic dose of insulin. This article focuses on the clinical problem of insulin resistance in insulin-dependent diabetic cats.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/20219486/