Peer-reviewed veterinary case report
Hypersomatotropism and Other Causes of Insulin Resistance in Cats.
- Journal:
- The Veterinary clinics of North America. Small animal practice
- Year:
- 2023
- Authors:
- Niessen, Stijn J M
- Affiliation:
- Royal Veterinary College London · United Kingdom
- Species:
- cat
Abstract
True insulin resistance should be differentiated from management-related difficulties (eg, short insulin duration, inappropriate insulin injection, inappropriate storage). Hypersomatotropism (HST) is the number one cause of insulin resistance in cats, with hypercortisolism (HC) occupying a more distant second place. Serum insulinlike growth factor-1 is adequate for screening for HST, and screening at the time of diagnosis, regardless of presence of insulin resistance, is advocated. Treatment of either disease centers on removal of the overactive endocrine gland (hypophysectomy, adrenalectomy) or inhibition of the pituitary or adrenal glands by using drugs such as trilostane (HC), pasireotide (HST, HC) or cabergoline (HST, HC).
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/36906467/