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Peer-reviewed veterinary case report

Equine cellular therapy--from stall to bench to bedside?

Journal:
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Year:
2013
Authors:
Burk, Janina et al.
Affiliation:
Faculty of Veterinary Medicine · Germany
Species:
horse

Plain-English summary

This research discusses the exciting advances in using stem cells to treat horses, which is important not just for veterinary medicine but also for potential human treatments. While there have been significant achievements in applying stem cell therapy to help horses with orthopedic issues, scientists are still working on better understanding the specific types of stem cells found in horses. The study emphasizes the need for improved communication between veterinarians and scientists to enhance these therapies. Overall, while progress is being made, more work is needed to fully understand and utilize equine stem cells effectively.

Abstract

Pioneering clinical stem cell research is being performed in the horse, a recipient of cutting edge veterinary medicine as well as a unique animal model, paving the way for human medical applications. Although demonstrable progress has been made on the clinical front, in vitro characterization of equine stem cells is still in comparatively early stages. To translate the promising results of clinical stem cell therapy in the horse, advances must be made in the characterization of equine stem cells. Aiming to improve communication between veterinarians and other natural scientists, this review gives an overview of veterinary "bedside" achievements, focusing on stem cell therapies in equine orthopedics as well as the current state of in vitro characterization of equine multipotent mesenchymal stromal cells (MSCs) and equine embryonic stem cells (ESCs).

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23081833/