Peer-reviewed veterinary case report
Diagnosis and Prognosis of Canine Cutaneous Mast Cell Tumors.
- Journal:
- The Veterinary clinics of North America. Small animal practice
- Year:
- 2019
- Authors:
- Kiupel, Matti & Camus, Melinda
- Affiliation:
- Michigan State University Veterinary Diagnostic Laboratory · United States
- Species:
- dog
Plain-English summary
Canine cutaneous mast cell tumors (MCTs) are one of the most common skin tumors in dogs, but they can behave very differently from one case to another. This review explains how veterinarians diagnose and predict the behavior of these tumors using different methods, including examining cells under a microscope and looking for specific markers that can indicate how aggressive the tumor might be. It also covers how to check if the tumor has spread to nearby lymph nodes or if it has clear surgical margins. Overall, the review highlights the importance of using a combination of tests to get the best understanding of these tumors.
Abstract
Canine cutaneous mast cell tumors (MCTs) are among the most common canine cutaneous tumors, with highly variable biological behavior. This review describes in detail current approaches for cytologic and histologic diagnosis and prognosis, including advantages and limitations of cytologic and histologic grading and utilization of molecular markers, for example, Ki67, AgNORs, KIT expression, and c-Kit mutations, for a more accurate detection of aggressive MCTs. Furthermore, the current approach to evaluate surgical margins and spread to local lymph nodes is discussed.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31178200/