Peer-reviewed veterinary case report
Diabetes mellitus, hyperadrenocorticism, and hypothyroidism in a dog.
- Journal:
- Journal of the American Animal Hospital Association
- Year:
- 1998
- Authors:
- Hess, R S & Ward, C R
- Affiliation:
- Department of Clinical Studies · United States
- Species:
- dog
Plain-English summary
A six-year-old spayed female mixed-breed dog was found to have three hormonal disorders at the same time: diabetes mellitus (a condition where the body can't properly use sugar), hyperadrenocorticism (a condition where the body produces too much cortisol), and hypothyroidism (a condition where the thyroid doesn't produce enough hormones). She showed signs like peeing and drinking a lot, eating more than usual, and losing weight. After starting treatment, her symptoms and blood test results improved significantly. This case is quite rare, as there haven't been any similar reports in the veterinary literature.
Abstract
An unusual combination of three endocrinopathies found in one dog is described. A six-year-old, spayed female, mixed-breed dog presented with polyuria, polydipsia, polyphagia, and weight loss. She was diagnosed with diabetes mellitus but was suspected of having insulin resistance and was diagnosed subsequently with hyperadrenocorticism. Persistent hypercholesterolemia led to the suspicion and eventual diagnosis of hypothyroidism. The dog has responded well to medical therapy, and her clinical signs and biochemical changes have resolved. A literature search did not identify a similar-reported polyendocrinopathy.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/9590447/