Peer-reviewed veterinary case report
Clostridioides difficile infection in dogs with chronic-recurring diarrhea responsive to dietary changes.
- Journal:
- Anaerobe
- Year:
- 2018
- Authors:
- Silva, Rodrigo Otávio Silveira et al.
- Affiliation:
- Veterinary School · Brazil
- Species:
- dog
Plain-English summary
In this study, five dogs with ongoing diarrhea tested positive for a bacterial infection called Clostridioides difficile (CDI), but they did not get better after being treated with a medication called metronidazole. One of the dogs had a procedure called a colonoscopy, which showed inflammation in the colon. However, all five dogs fully recovered after their diets were changed. This suggests that CDI can happen in dogs with other gut issues, and that changes in gut bacteria should be considered in dogs with long-lasting diarrhea who test positive for this infection.
Abstract
Five dogs with chronic-recurring diarrhea were positive for Clostridioides difficile infection (CDI), but were unresponsive to treatment with metronidazole. One of these animals was subjected to a colonoscopy, which revealed eosinophilic infiltration of the colon. All five animals completely recovered after dietary changes. The present work suggests that CDI might occur in dogs with other intestinal alterations. In addition, this report suggests that dysbiosis should be considered in animals that have chronic-recurring diarrhea and test positive for C. difficile.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/29621604/