Peer-reviewed veterinary case report
Chronic interstitial pneumonia with features of organizing pneumonia in an adult horse.
- Journal:
- Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
- Year:
- 2020
- Authors:
- Carrillo, Miguel F et al.
- Affiliation:
- Plataforma de Investigació
- Species:
- horse
Plain-English summary
A 22-year-old American Quarter Horse gelding was having ongoing breathing problems that got worse over time. X-rays showed unusual growths in his lungs, and unfortunately, he was euthanized for further examination. Tests on lung samples revealed a condition called organizing pneumonia, which involves thickening of lung tissue and scarring, but the exact cause of this issue wasn't identified. The findings suggest that there are other possible reasons for chronic lung problems in horses besides the commonly known equid herpesvirus 5, including other viral or bacterial infections or long-term exposure to toxins. In this case, the treatment options were limited, and the horse did not survive.
Abstract
A 22-y-old American Quarter Horse gelding was presented with a history of chronic progressive respiratory problems and a diffuse pulmonary nodular pattern in thoracic radiographs. The horse was euthanized, and 4 formalin-fixed samples of lung were submitted for histopathology. There were multifocal areas of marked thickening of alveolar septa as a result of proliferation of myofibroblasts embedded in fibromyxoid matrix (interpreted as "Masson bodies"), focal areas of fibrosis, and numerous papillary projections of connective tissue into bronchioles. A diagnosis of organizing pneumonia was reached. No etiology was found for this lesion. It is important to consider causes of chronic interstitial pneumonia with fibrosis in horses other than equid herpesvirus 5, such as complicated viral or bacterial pneumonia or chronic toxicoses.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/32687009/