Peer-reviewed veterinary case report
Severe pulmonary disease due to multisystemic eosinophilic epitheliotropic disease in a horse.
- Journal:
- Veterinary pathology
- Year:
- 2006
- Authors:
- Singh, K et al.
- Affiliation:
- Department of Veterinary Pathobiology · United States
- Species:
- horse
Plain-English summary
A 17-year-old Quarter Horse mare was found to have a serious lung condition called multisystemic eosinophilic epitheliotropic disease, which was identified through tissue samples. She had been struggling with breathing problems for a long time. During the examination after her death, her lungs showed many small, round lumps, and similar lumps were also found in her liver and lymph nodes. These lumps were made up of a type of inflammation involving a specific white blood cell called eosinophils. Unfortunately, the diagnosis indicated a severe condition without a clear cause, and it highlights the complexity of her illness.
Abstract
Multisystemic eosinophilic epitheliotropic disease was diagnosed histologically in a 17-year-old Quarter Horse intact mare that was presented with a chronic history of respiratory distress. At necropsy, the lungs were poorly collapsed and the pulmonary parenchyma contained innumerable, discrete, spherical nodules in a miliary pattern. A few similar nodules were scattered in the liver and the renal lymph nodes. Histologically, these nodules consisted of fibrosing eosinophilic granulomas. Based on histologic findings and the absence of an etiologic agent, a diagnosis of multisystemic eosinophilic epitheliotropic disease was made.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16537938/