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Peer-reviewed veterinary case report

BSE-associated prion-amyloid cardiomyopathy in primates.

Journal:
Emerging infectious diseases
Year:
2013
Authors:
Krasemann, Susanne et al.
Affiliation:
University Medical Center Hamburg-Eppendorf · Germany

Abstract

Prion amyloidosis occurred in the heart of 1 of 3 macaques intraperitoneally inoculated with bovine spongiform encephalopathy prions. This macaque had a remarkably long duration of disease and signs of cardiac distress. Variant Creutzfeldt-Jakob disease, caused by transmission of bovine spongiform encephalopathy to humans, may manifest with cardiac symptoms from prion-amyloid cardiomyopathy.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23735198/