Peer-reviewed veterinary case report
An unusual lipomatous brain mass in a Golden Retriever dog.
- Journal:
- Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
- Year:
- 2015
- Authors:
- Scott, Steven J et al.
- Affiliation:
- Canada (Godson)Western College of Veterinary Medicine · Australia
- Species:
- dog
Plain-English summary
A 9-year-old Golden Retriever was taken to the veterinary hospital because he had been having grand mal seizures (a type of severe seizure) for three weeks. Sadly, he was euthanized after his condition did not improve. During the examination after his passing, the veterinarians found a firm mass in his brain that was pressing on important areas. This mass was made up of fat cells and other supportive tissue, and it was identified as a type of growth called an intracranial lipomatous hamartoma, which is unusual in dogs. Unfortunately, the treatment options were limited, and the outcome was not favorable.
Abstract
A 9-year-old Golden Retriever dog was presented to the Veterinary Medical Center with a 3-week history of grand mal seizures and was subsequently euthanized. At autopsy, a discrete, firm, expansile mass was found in the right pyriform lobe, which compressed the ipsilateral hippocampus, thalamus, and cerebral cortex. Histologically, the mass was composed of well-differentiated adipose tissue supported by fibrous and mucinous stroma. Adipocytes exhibited strong immunoreactivity for vimentin and were negative for pancytokeratin (AE1/AE3), glial fibrillary acidic protein, neuron-specific enolase, and synaptophysin. These findings are most compatible with an intracranial lipomatous hamartoma, which is an extraparenchymal lesion that has been identified in several species. The current report describes an intracerebral lipomatous hamartoma in a veterinary species.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/26450836/