Peer-reviewed veterinary case report
Water homeostasis and diabetes insipidus in horses.
- Journal:
- The Veterinary clinics of North America. Equine practice
- Year:
- 2011
- Authors:
- Schott, Harold C
- Affiliation:
- Department of Large Animal Clinical Sciences · United States
- Species:
- horse
Abstract
Diabetes insipidus (DI) is a rare disorder of horses characterized by profound polyuria and polydipsia (PU/PD), which can be caused by loss of production of arginine vasopressin (AVP). This condition is termed neurogenic or central DI. DI may also develop with absence or loss of AVP receptors or activity on the basolateral membrane of collecting-duct epithelial cells. This condition is termed nephrogenic DI. Equine clinicians may differentiate true DI from more common causes of PU/PD by a systematic diagnostic approach. DI may not be a correctable disorder, and supportive care of affected horses requires an adequate water source.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21392661/