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Peer-reviewed veterinary case report

Virulence of Curvularia in a murine model.

Journal:
Mycoses
Year:
2013
Authors:
Paredes, Katihuska et al.
Affiliation:
Unitat de Microbiologia · Spain
Species:
rodent

Abstract

We have evaluated the virulence of two clinically relevant species of Curvularia; Curvularia spicifera and C. hawaiiensis, using an experimental model of disseminated infection in immunocompromised mice. Several inocula were tested over a range 1 × 10(3) -1 × 10(6) colony-forming units/animal. Both species had a similar behaviour, producing a high mortality. Tissue burden and histopathology studies demonstrated that lung was the organ most affected.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23437873/