Peer-reviewed veterinary case report
Use of new adjuvants in an emergency vaccine against foot-and-mouth disease virus: evaluation of conferred immunity.
- Journal:
- Developments in biologicals
- Year:
- 2004
- Authors:
- Quattrocchi, V et al.
- Affiliation:
- Virology Institute
- Species:
- rodent
Abstract
The ability of an emergency adjuvanted FMDV vaccine to elicit early protective immune response in mice was examined. We studied the efficacy of several adjuvants to induce such protection. The aqueous IMS1313 plus inactivated FMDV induce a higher protective immune response than the vaccine with inactivated virus alone at seven days post vaccination (dpv). Mice vaccinated with this formula showed higher lymphoproliferative index values and higher IL-2, IL-4 and IFNgamma levels than the controls.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15742663/