Peer-reviewed veterinary case report
Ultra-highly sensitive and wash-free bio-detection of H5N1 virus by immunomagnetic reduction assays.
- Journal:
- Journal of virological methods
- Year:
- 2008
- Authors:
- Yang, S Y et al.
- Affiliation:
- Institute of Electro-optical Science and Technology
- Species:
- bird
Abstract
A platform for assaying avian influenza H5N1 viruses that involves measuring the ac immunomagnetic reduction of a magnetic reagent mixed with a detected sample is developed. The magnetic reagent contained magnetic nanoparticles coated with antibodies. To achieve an ultra-high sensitivity assay, a system utilizing a high-transition-temperature superconducting quantum interference device was used to sense the immunomagnetic reduction of the reagents. The results confirmed the ultra-high sensitivity of the immunomagnetic reduction assay on H5N1.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18760307/