Peer-reviewed veterinary case report
Treatment of coccidioidomycosis osteomyelitis with itraconazole in a horse. A brief report.
- Journal:
- Journal of veterinary internal medicine
- Year:
- 1992
- Authors:
- Foley, J P & Legendre, A M
- Affiliation:
- Southwest Equine Hospital
- Species:
- horse
Plain-English summary
A Quarter Horse filly was treated with itraconazole, a medication used for certain fungal infections, to address coccidioidomycosis, which is a type of fungal disease. After 90 days of treatment, she was nearly back to normal. However, five months after stopping the medication, she experienced severe neck pain and some neurological issues due to a return of the infection. She was given itraconazole again for another six months, and her condition improved significantly, remaining stable and normal for the past two years. There were no signs of any harmful effects from the medication.
Abstract
Itraconazole, a tricyclic azole effective against a number of deep mycotic diseases, was used to treat a Quarter Horse filly with coccidioidomycosis. The horse was almost normal after 90 days of treatment. Five months after discontinuing itraconazole treatment, the filly had severe neck pain and neurologic signs from recurrence of coccidioidomycosis and was treated with itraconazole for an additional 6 months. Her clinical condition improved to almost normal and the filly has remained normal for 2 years. There was no evidence of drug toxicity.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/1336557/