Transarterial ductal occlusion using the Amplatz Canine Duct Occluder in 40 dogs.

Abstract

OBJECTIVES: Describe the result of patent ductus arteriosus (PDA) occlusion using the Amplatz Canine Duct Occluder (ACDO) in 40 dogs. ANIMALS, MATERIAL AND METHODS: Records of the first 41 dogs at Texas A&M University in which ductal occlusion with an ACDO was attempted were reviewed. RESULTS: Appropriate device release was achieved in 40 of 41 dogs. Post-release angiography in 39 dogs documented complete occlusion in 27 dogs, trivial residual flow in 7, mild residual flow in 1 and moderate residual flow in 4; angiography was not recorded in one dog. The following day transthoracic color Doppler echocardiography documented complete occlusion in all 40 dogs. One dog required a larger device than could be deployed through the largest sheath accommodated by the femoral artery and the PDA was subsequently closed by surgical ligation. CONCLUSIONS: Ductal occlusion using an ACDO has a high rate of initial and 24-h complete occlusion. Ductal occlusion using an ACDO is a safe and efficacious therapy for PDA in dogs. This report confirms the positive clinical outcome of the original report in a large cohort of dogs.