Peer-reviewed veterinary case report
Therapeutic Effects of Bacteroides fragilis Vesicles in a Model of Chemically Induced Colitis in Rats.
- Journal:
- Bulletin of experimental biology and medicine
- Year:
- 2024
- Authors:
- Shagaleeva, O Yu et al.
- Affiliation:
- Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency
- Species:
- rodent
Abstract
The anti-inflammatory properties of Bacteroides fragilis vesicles were studied in a rat model of dextran sodium sulfate-induced colitis. According to the histology results, addition of B. fragilis vesicles to the therapy promoted colon repair. Evaluation of the disease activity index confirms the high rate of colon recovery: against the background of vesicle administration, the absence of blood in stool, normal stool consistency, and body weight normalization were observed.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/39343844/