The use of surgical glue and sutures in the aponeurosis synthesis of the abdominal wall in Wistar rats.

Abstract

<h4>Background</h4>Adequate closure of the abdominal wall determines the success of the surgery.<h4>Aims</h4>The aim of this study was to study the healing of the abdominal wall of rats by comparing the use of surgical glue (2-octyl cyanoacrylate) with polypropylene 3.0 thread and poliglecaprone 3.0 thread.<h4>Methods</h4>A total of 60 Wistar rats were divided into two groups: Group 30 and Group 90. Each group was subdivided into three subgroups, surgical glue subgroup (C1), polypropylene subgroup (C2), and poliglecaprone subgroup (C3). An incision was made in the aponeurosis of the abdominal wall while maintaining the integrity of the parietal peritoneum. The 3 subgroups of 10 animals were euthanized on the 30th and 90th postoperative days. The abdominal wall fragments were submitted to macroscopic, histological, and tensiometric analysis.<h4>Results</h4>Macroscopic analysis did not show any abnormality. Tensiometry on the 30th postoperative day showed a mean rupture tension of 30.98N in subgroup C1, 27.90N in subgroup C2, and 23.90N in subgroup C3. On the 90th postoperative day, the mean rupture tension was 30.05N in subgroup C1, 44.42N in subgroup C2, and 34.78N in subgroup C3.<h4>Conclusions</h4>The synthesis of the abdominal aponeurosis performed with surgical glue (2-octyl cyanoacrylate) showed adequate resistance to rupture tension to maintain its integrity when compared with the synthesis with polypropylene thread or poliglecaprone thread, with both methods being equally effective.