Peer-reviewed veterinary case report
The first report of terbinafine resistance Microsporum canis from a cat.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2018
- Authors:
- Hsiao, Yun-Hsia et al.
- Affiliation:
- Asian Veterinary Specialist Referral Center
Plain-English summary
A 2-year-old exotic shorthair cat was brought in because it had bald patches and some mild scaling on its body. Tests confirmed that it had a fungal infection called Microsporum canis (M. canis), which is a type of skin infection. The veterinarians used special tests to identify the fungus and check how resistant it was to antifungal medications. They found that the fungus was resistant to terbinafine but sensitive to itraconazole. The cat was successfully treated and cured of the infection with itraconazole.
Abstract
A 2-year-old, exotic shorthair cat presented with baldness and mild scaling on trunk that was confirmed as Microsporum canis (M. canis) infection by the following methods. Wood's lamp and trichogram were used to demonstrate fungal elements suggestive of dermatophytosis consistent with M. canis. Dermatophyte test medium (DTM) and polymerase chain reaction (PCR) were used for identification. E-test and broth microdilution test were then utilized to estimate antifungal minimal inhibitory concentrations (MICs) towards ITZ and TRF respectively. The strain was isolated from the patient and revealed TRF MIC >32 µg/ml and ITZ MIC 0.023 µg/ml. Patient was cured of dermatophytosis with systemic ITZ.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/29657238/