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Peer-reviewed veterinary case report

The effects of voluntary, involuntary, and forced exercises on motor recovery in a stroke rat model.

Journal:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Year:
2011
Authors:
Ke, Zheng et al.
Affiliation:
the Department of Health Technology and Informatics · China
Species:
rodent

Abstract

Stroke rehabilitation with different exercise paradigms has been investigated, but a comparison study on motor recovery after voluntary, involuntary, and forced exercises is limited. The current study used a rat brain ischemia model to investigate the effects of voluntary wheel running, involuntary muscle movement caused by functional electrical stimulation (FES), and forced treadmill exercise on motor recovery and brain BDNF changes. The results showed that voluntary exercise is the most effective intervention in upregulating the hippocampal BDNF level, and facilitating motor recovery after brain ischemia.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22256251/