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Peer-reviewed veterinary case report

Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia.

Journal:
Infection and immunity
Year:
2007
Authors:
Bubeck Wardenburg, Juliane et al.
Affiliation:
Department of Microbiology · United States
Species:
rodent

Abstract

A model of Staphylococcus aureus-induced pneumonia in adult, immunocompetent C57BL/6J mice is described. This model closely mimics the clinical and pathological features of pneumonia in human patients. Using this system, we defined a role for S. aureus strain Newman surface proteins and secreted exotoxins in pneumonia-related mortality.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17101657/