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Peer-reviewed veterinary case report

Successful use of topical mitomycin C for the treatment of a putative neoplastic vascular mass on the nictitating membrane of a dog.

Journal:
Australian veterinary journal
Year:
2020
Authors:
Seavers, A et al.
Affiliation:
Oak Flats Veterinary Clinic · United Kingdom
Species:
dog

Abstract

A nine-year-old female desexed Great Dane presented with a painful, proliferative, soft red putative neoplastic vascular mass on the nictitating membrane. Three 7-day cycles of the topical cytotoxic drug mitomycin C 0.04%, applied four times daily to the lesion using a low-dose alternate-week pulse therapy, brought about rapid remission of the lesion. The lesion was still in remission at time of euthanasia some 13 months later.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/31919837/