Peer-reviewed veterinary case report
Successful hemodialysis treatment of a Quarter Horse mare with silver maple leaf toxicity and acute kidney injury.
- Journal:
- Journal of veterinary internal medicine
- Year:
- 2024
- Authors:
- Pinnell, Erin F et al.
- Affiliation:
- Department of Veterinary Clinical Sciences · United States
- Species:
- horse
Plain-English summary
A Quarter Horse mare was brought in because she was very tired and had dark-colored urine for about 12 hours. She was found to have silver maple leaf toxicity, which caused damage to her kidneys and her blood. The treatment included a blood transfusion, fluids given through an IV, antibiotics, and oxygen support. When her kidney issues didn't improve with standard treatment, she underwent hemodialysis, a process that helps filter toxins from the blood. After two sessions over three days, her kidney function improved significantly, and she was able to go home. Six months later, her kidney levels were still normal, showing that the treatment was successful.
Abstract
An adult American Quarter Horse mare presented for pigmenturia and lethargy of 12 hours' duration and was diagnosed with silver maple leaf toxicity. The mare had intravascular hemolysis and azotemia. The mare was treated with a transfusion of whole blood, fluids administered IV, antibiotics, oxygen insufflation, and supportive care. The azotemia persisted despite conventional medical management and hemodialysis was elected. After 2 intermittent hemodialysis treatments over 3 days, the azotemia almost resolved, clinical signs improved, and the mare was discharged. The blood urea nitrogen, creatinine, and electrolyte concentrations remained normal 6 months later after examination by the referring veterinarian. Hemodialysis treatment can be feasible in horses if equipment and expertise are available and should be considered as a treatment option if indicated.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/38682859/