Peer-reviewed veterinary case report
Sterile nodular panniculitis in five horses.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1990
- Authors:
- Karcher, L F et al.
- Affiliation:
- Department of Clinical Sciences · United States
- Species:
- horse
Plain-English summary
Five horses were diagnosed with a condition called sterile nodular panniculitis, which means they developed multiple lumps under their skin that would come and go over time. These lumps were mostly found on their bodies, necks, and upper legs. The diagnosis was confirmed by taking a sample of one of the lumps and ruling out any infections. Treatment involved giving them high doses of a type of medication called glucocorticoids, which helped one horse completely recover, while two others needed ongoing treatment to manage their symptoms. Unfortunately, the treatment did not help the last two horses at all.
Abstract
Sterile nodular panniculitis was diagnosed in 5 horses. Physical abnormalities were predominantly limited to cutaneous changes, consisting of multiple subcutaneous nodules that had a tendency to wax and wane over time and were commonly distributed over the trunk, neck, and proximal portion of the limbs. In each horse, the diagnosis was confirmed by excisional biopsy of a nodule and by exclusion of infective causes of panniculitis on the basis of negative culture results and special stain application to skin specimens. Treatment with immunosuppressive doses of glucocorticoids was curative in 1 horse, was required on a daily or alternate-day schedule in 2 others to keep the skin clear, and had no effect on the disease in the remaining 2 horses.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/2351604/