Peer-reviewed veterinary case report
SIV infection in natural hosts: resolution of immune activation during the acute-to-chronic transition phase.
- Journal:
- Microbes and infection
- Year:
- 2011
- Authors:
- Mir, Kiran D et al.
- Affiliation:
- Seattle Biomedical Research Institute · United States
Abstract
SIV-infected natural hosts do not progress to clinical AIDS yet display high viral replication and an acute immunologic response similar to pathogenic SIV/HIV infections. During chronic SIV infection, natural hosts suppress their immune activation, whereas pathogenic hosts display a highly activated immune state. Here, we review natural host SIV infections with an emphasis on specific immune cells and their contribution to the transition from the acute-to-chronic phases of infection.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/20951225/