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Peer-reviewed veterinary case report

Simultaneous occurrence of inflammatory bowel disease and trichomonosis in a Maine coon cat.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
2022
Authors:
Santos, César A R et al.
Affiliation:
Department of Veterinary Clinic (Santos · Brazil
Species:
cat

Plain-English summary

A 2-year-old spayed female Maine coon cat was taken to the vet because she was eating less than usual, not growing properly, and had been experiencing severe diarrhea that was bloody and had a bad smell. This diarrhea had started when she was 4 months old and got worse in the days leading up to her vet visit. The vet found that her abdomen was painful and tests showed thickening of her intestines and swollen lymph nodes. A biopsy revealed inflammation in her intestines, and tests confirmed she had both inflammatory bowel disease (a condition causing inflammation in the digestive tract) and trichomonosis (a parasitic infection). She was treated with a special diet, an omega-3 supplement, and medication to reduce inflammation, along with another medication to address the trichomonosis. After 6 months of treatment, she was doing well and appeared healthy at her follow-up visit.

Abstract

A 2-year-old, 4.2 kg, spayed female, Maine coon cat was referred to the veterinary hospital for evaluation of hyporexia, slow growth, and chronic, intermittent, mucoid, bloody, voluminous, and fetid diarrhea. The diarrhea had been observed since the cat was acquired from a cattery at 4 months of age; with acute worsening in the 5 d before presentation. Abdominal palpation revealed moderate pain. Ultrasonographic examination showed thickening of the jejunal wall and ileal loops, increased echogenicity of the jejunal mucosa, and enlargement of the jejunal and ileocolic lymph nodes. Histopathology of full-thickness intestinal biopsies showed moderate, diffuse, lymphoplasmacytic, erosive enteritis with hemorrhage and edema. Diffuse, lymphoplasmacytic, erosive colitis with mild, interstitial fibrosis and hemorrhage was also noted. The ileocecal lymph node biopsy showed eosinophilic lymphadenitis. Based on the immunohistochemical evaluation of intestinal samples with CD3 and CD79a antibodies, a diagnosis of lymphoma was ruled out. Fecal polymerase chain reaction testing was positive for. Based on these results, inflammatory bowel disease and trichomonosis were diagnosed. Treatment for the cat included a hypoallergenic diet and an oral omega-3 fatty acid supplement, in conjunction with prednisolone, to manage the inflammatory bowel disease. Ronidazole was administered to target the. The cat was clinically normal during a follow-up examination after 6 months of treatment.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/35237015/