Peer-reviewed veterinary case report
Simian immunodeficiency virus infection and flow cytometric characterization of Japanese macaque (Macaca fuscata) hematopoietic cells.
- Journal:
- Journal of medical primatology
- Year:
- 2020
- Authors:
- Tsukamoto, Tetsuo et al.
- Affiliation:
- Kumamoto University · Japan
Abstract
We characterized Japanese macaque (Macaca fuscata) hematopoietic cells using flow cytometry and identified 28 cross-reactive anti-human antibody clones. Furthermore, productive infection of peripheral T lymphocytes with simian immunodeficiency virus (SIV) in vitro was confirmed by intracellular SIV p27 staining. This study could facilitate using Japanese macaques as models for human hematological and immunological disorders and infectious diseases.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31907946/