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Peer-reviewed veterinary case report

Shock wave treatment improves nerve regeneration in the rat.

Journal:
Muscle & nerve
Year:
2013
Authors:
Mense, Siegfried & Hoheisel, Ulrich
Affiliation:
Department of Neurophysiology · Germany
Species:
rodent

Abstract

INTRODUCTION: The aims of the experiments were to: (1) determine whether low-energy shock wave treatment accelerates the recovery of muscle sensitivity and functionality after a nerve lesion; and (2) assess the effect of shock waves on the regeneration of injured nerve fibers. METHODS: After compression of a muscle nerve in rats the effects of shock wave treatment on the sequelae of the lesion were tested. In non-anesthetized animals, pressure pain thresholds and exploratory activity were determined. The influence of the treatment on the distance of nerve regeneration was studied in immunohistochemical experiments. RESULTS: Both behavioral and immunohistochemical data show that shock wave treatment accelerates the recovery of muscle sensitivity and functionality and promotes regeneration of injured nerve fibers. CONCLUSION: Treatment with focused shock waves induces an improvement of nerve regeneration in a rodent model of nerve compression.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23505053/