Peer-reviewed veterinary case report
Sequences of papillomavirus DNA in equine sarcoids.
- Journal:
- Equine veterinary journal
- Year:
- 1985
- Authors:
- Trenfield, K et al.
- Species:
- horse
Abstract
DNA was extracted from 14 equine sarcoids, electrophoresed and hybridised with a radioactively labelled probe of bovine papillomavirus type I (BPV 1) DNA under conditions of low stringency. Twelve sarcoids contained sequences of DNA that hybridised with the probe and that comigrated with BPV 2 DNA. The viral DNAs in four of these sarcoids differed from BPV 1 and BPV 2 DNA on restriction endonuclease analysis. One of four cell lines derived from sarcoids also contained BPV 1 related DNA. The results confirm the frequent presence in equine sarcoids of unintegrated papillomaviral DNA and suggest a role for papillomavirus infection in this disease.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/3000762/