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Peer-reviewed veterinary case report

Secondary tumoural valvulopathy in a dog.

Journal:
Acta veterinaria Hungarica
Year:
2009
Authors:
Jakab, Csaba et al.
Affiliation:
Department of Pathology and Forensic Veterinary Medicine
Species:
dog

Abstract

This short report describes a case of tricuspid valvular metastasis of canine disseminated histiocytic sarcoma in a 9-year-old female Rottweiler. Immunohistochemically the malignant neoplastic cells gave a strong reaction for vimentin and lysozyme, and showed negativity for serotonin, CD3, CD79a and cytokeratin. The intratumoural microvessels were detected by immunohistochemistry using CD31 and claudin-5. This appears to be the first report of a valvular metastasis of canine malignant histiocytosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19457774/