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Peer-reviewed veterinary case report

Response evaluation criteria for peripheral nodal lymphoma in dogs (v1.0)--a Veterinary Cooperative Oncology Group (VCOG) consensus document.

Journal:
Veterinary and comparative oncology
Year:
2010
Authors:
Vail, D M et al.
Affiliation:
The School of Veterinary Medicine and The Carbone Comprehensive Cancer Center · United States
Species:
dog

Plain-English summary

There hasn't been a standard way to measure how well treatments for lymphoma in dogs are working, which makes it hard to compare different treatment methods. A group of veterinary cancer specialists has come together to create a set of guidelines that can be used to evaluate treatment responses in dogs with lymphoma, particularly when they have swollen lymph nodes. These guidelines are based on methods used for humans but are tailored for dogs and are designed to be simple and easy to use in regular veterinary practice. The hope is that these guidelines will be widely adopted, helping veterinarians compare different treatment options for dogs with this condition.

Abstract

Standardized assessment of response to therapy for lymphoma in dogs is lacking, making critical comparisons of treatment protocols difficult. This Veterinary Cooperative Oncology Group (VCOG) consensus document, based on the recommendations of a subcommittee of ACVIM board-certified veterinary oncologists, was unanimously adopted at the 29th Annual Conference of the Veterinary Cancer Society (VCS) by the VCOG membership. It has integrated guidance from the response assessment criteria established for lymphoma in human patients using standards available in routine veterinary oncology practices that are simple, repeatable and consistently applicable. These guidelines are intended only for use in dogs, where peripheral lymphadenopathy represents the principal component of their disease and as such do not critically assess extranodal disease (e.g., primary cutaneous, central nervous system, gastrointestinal). It is hoped these guidelines will be widely adopted and serve to facilitate the comparison of current and future treatment protocols used in the therapy of dogs.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/20230579/