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Peer-reviewed veterinary case report

Rabbit Model for Superantigen-Mediated Lethal Pulmonary Disease.

Journal:
Methods in molecular biology (Clifton, N.J.)
Year:
2016
Authors:
Strandberg, Kristi L et al.
Affiliation:
Department of Microbiology · United States
Species:
rabbit

Abstract

Staphylococcus aureus is a highly significant cause of serious human infections in the USA. Many of these illnesses are mediated by interactions between the host immune system and staphylococcal superantigens (SAgs). Several of these severe staphylococcal infections are initiated in the lungs, making this an important site to study. Here, we describe the rabbit model for investigating the role of staphylococcal SAgs in pulmonary-associated lethal infection and intoxication.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/26676039/