Peer-reviewed veterinary case report
Proinflammatory cytokine expression in the early phase of Trypanosoma brucei rhodesiense infection in vervet monkeys (Cercopithecus aethiops).
- Journal:
- Infection and immunity
- Year:
- 2004
- Authors:
- Maina, Naomi et al.
- Affiliation:
- Kenya Trypanosomiasis Research Institute · United Kingdom
Abstract
A vervet monkey model of trypanosomiasis was used to study inflammatory cytokine responses in serum and cerebrospinal fluid (CSF). Gamma interferon levels were transiently up-regulated in serum between days 6 and 8 of infection, followed by a sustained up-regulation of tumor necrosis factor alpha (TNF-alpha) and soluble TNF receptor 1. At no time were these cytokines detectable in the CSF.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15102822/