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Peer-reviewed veterinary case report

Primary invasive ocular squamous cell carcinoma in a horse.

Journal:
Veterinary ophthalmology
Year:
2005
Authors:
Kaps, Simone et al.
Affiliation:
Department of Small Animals Ophthalmology Service
Species:
horse

Plain-English summary

A 12-year-old Haflinger gelding was taken to a veterinary hospital in Zurich because he had a light-pink raised growth on the edge of his left eye. After surgery to remove the mass and freezing treatment, it was confirmed to be squamous cell carcinoma, a type of skin cancer. Seven months later, a new smooth pink mass appeared in the cornea of the same eye, and tests showed it was growing into deeper layers of the eye. Ultimately, the eye was surgically removed, and further examination revealed that the cancer had invaded multiple parts of the eye. This case is significant as it is the first detailed report of this type of cancer affecting the cornea and other eye structures in horses.

Abstract

A 12-year-old Haflinger gelding was presented to the veterinary medical teaching hospital of the University of Zurich with a light-pink raised mass on the temporal limbus and conjunctiva of the left eye. Squamous cell carcinoma was confirmed histologically after keratectomy and cryotherapy. Seven months later, a smooth pink, progressively enlarging mass was observed within the cornea of the left eye. Ultrasonographically, the mass was not only infiltrating the corneal stroma but seemed to protrude into the anterior chamber. The globe was surgically removed and submitted for pathology. A histologic diagnosis of corneal ocular squamous cell carcinoma with deep stromal invasion, infiltration of the uveoscleral meshwork and iridocorneal angle and resulting intraocular extension was made. This is the first detailed description of a limbal squamous cell carcinoma with invasion into the cornea and uvea in the horse.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15910373/