Peer-reviewed veterinary case report
Primary hypothyroidism associated with leishmaniasis in a dog.
- Journal:
- Journal of the American Animal Hospital Association
- Year:
- 1999
- Authors:
- Cortese, L et al.
- Affiliation:
- Dipartimento di Scienze Cliniche Veterinarie · Italy
- Species:
- dog
Plain-English summary
A four-year-old male Yorkshire terrier was diagnosed with primary hypothyroidism, which means his thyroid gland wasn't producing enough hormones. This condition was linked to leishmaniasis, a disease caused by a parasite. Tests showed low levels of a thyroid hormone called T4, a poor response to a hormone that stimulates the thyroid, and high levels of another hormone called TSH. A biopsy of the thyroid revealed the presence of the leishmaniasis parasite along with signs of damage to the thyroid tissue. The outcome of the treatment for this condition is not specified in the abstract.
Abstract
A case of primary hypothyroidism associated with leishmaniasis is described in a four-year-old, male Yorkshire terrier. Clinical diagnosis of hypothyroidism was confirmed by a low baseline serum tetraiodothyronine (T4), a reduced response to thyroid-stimulating hormone (TSH) stimulation, an increased serum TSH concentration, and scintigraphic thyroid gland examination. Examination of a thyroid biopsy showed many Leishmania amastigotes, both inside and outside of macrophages, together with signs of follicular atrophy.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/10580908/