Peer-reviewed veterinary case report
Prevention of schizophrenia deficits via non-invasive adolescent frontal cortex stimulation in rats.
- Journal:
- Molecular psychiatry
- Year:
- 2020
- Authors:
- Hadar, Ravit et al.
- Affiliation:
- Department of Psychiatry and Psychotherapy · Germany
- Species:
- rodent
Abstract
Schizophrenia is a severe neurodevelopmental psychiatric affliction manifested behaviorally at late adolescence/early adulthood. Current treatments comprise antipsychotics which act solely symptomatic, are limited in their effectiveness and often associated with side-effects. We here report that application of non-invasive transcranial direct current stimulation (tDCS) during adolescence, prior to schizophrenia-relevant behavioral manifestation, prevents the development of positive symptoms and related neurobiological alterations in the maternal immune stimulation (MIS) model of schizophrenia.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/30692610/