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Peer-reviewed veterinary case report

Plasmodium fieldi: observations on the Hackeri and ABI strains in Macaca mulatta monkeys and mosquitoes.

Journal:
The American journal of tropical medicine and hygiene
Year:
2009
Authors:
Collins, William E et al.
Affiliation:
Division of Parasitic Diseases and Scientific Resources Branch · United States

Abstract

Macaca mulatta monkeys infected with the Hackeri strain of Plasmodium fieldi had maximum parasite counts ranging from 1,300 to 301,320/microL. In 43 intact animals infected with the ABI strain, the maximum parasite counts ranged from 672 to 57,189/microL (median = 15,100/microL); in 46 splenectomized monkeys, the maximum parasite count ranged from 660 to 350,000/microL (median = 52,245/microL). Transmission through Anopheles dirus mosquitoes was obtained on 11 occasions with pre-patent periods of 9-14 days. Relapses occurred between two and eight times during a 1-year period. P. fieldi has potential for testing prophylactic and radical curative drugs.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19407117/