Peer-reviewed veterinary case report
Plasma histamine concentration and histamine detection in peripheral blood eosinophils in cats.
- Journal:
- Journal of feline medicine and surgery
- Year:
- 2006
- Authors:
- Kadoya, Michiyo et al.
- Affiliation:
- Department of Veterinary Internal Medicine · Japan
- Species:
- cat
Abstract
Plasma histamine levels were measured in 11 clinically healthy cats and 15 cats with allergic dermatitis. Histamine levels were markedly elevated in 5/15 allergic cats. A calcium ionophore, A23187, stimulates histamine release from feline peripheral blood cells. Immunostaining of blood smears from clinically healthy cats revealed that approximately 10% of eosinophils possessed histamine-containing granules. These results indicate that some peripheral eosinophils in cats contain histamine and can release histamine by appropriate stimulation.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16650786/