Peer-reviewed veterinary case report
Pharmacologic treatment of priapism in two horses.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1991
- Authors:
- Wilson, D V et al.
- Affiliation:
- Department of Large Animal Clinical Sciences · United States
- Species:
- horse
Plain-English summary
In this study, two horses developed a condition called priapism, which is a prolonged and painful erection, during anesthesia. They were treated with a medication called benztropine mesylate, which was given through an IV. After receiving the treatment, both horses quickly showed improvement, and there were no side effects noted. Although the exact reasons for priapism can be unclear, this medication worked well in these cases. Overall, the treatment was successful in resolving the issue for both horses.
Abstract
Benztropine mesylate was used successfully to treat priapism that developed during anesthesia in 2 horses. After IV injection, there was a rapid resolution of signs in both horses, and no side effects were observed. The choice of an effective method to treat priapism is challenging because precise causes in most patients have not been well-defined. Benztropine mesylate is a synthetic compound resulting from the combination of the active portions of atropine and diphenhydramine, and is believed effective because of its central acetyl-choline-antagonizing properties.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/1752772/