Peer-reviewed veterinary case report
Pharmacogenomics of Cytauxzoon felis cytochrome b: implications for atovaquone and azithromycin therapy in domestic cats with cytauxzoonosis.
- Journal:
- Journal of clinical microbiology
- Year:
- 2013
- Authors:
- Schreeg, Megan E et al.
- Affiliation:
- North Carolina State University College of Veterinary Medicine · United States
- Species:
- cat
Abstract
Cytauxzoon felis, an emerging virulent protozoan parasite that infects domestic cats, is treated with atovaquone and azithromycin (A&A). Atovaquone targets parasite cytochrome b. We characterized the C. felis cytochrome b gene (cytb) in cats with cytauxzoonosis and found a cytb genotype that was associated with survival in A&A-treated cats.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/23784135/