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Peer-reviewed veterinary case report

Periocular neurofibrosarcoma in a horse.

Journal:
Veterinary ophthalmology
Year:
2001
Authors:
Strubbe, D T
Affiliation:
Animal Eye Specialty Clinic · United States
Species:
horse

Plain-English summary

A 5-year-old Thoroughbred mare had a large lump above her right eye that had been growing slowly for a year. The lump was surgically removed, and then a special chemotherapy drug called cisplatin was injected directly into the area three times over the next couple of months. After 15 months of follow-up, there were no signs that the lump had come back. The tests on the lump showed it was a type of tumor called neurofibrosarcoma. Overall, the treatment was successful.

Abstract

A periocular neurofibrosarcoma was debulked and treated with intralesional cisplatin in a 5-year-old Thoroughbred mare. The horse presented with a 1-year history of a large slowly progressing subcutaneous mass over the right supraorbital process. The mass was surgically debulked, and intralesional cisplatin (1.0 mg/cm3) was injected in 3 doses at 2 weeks, 5 weeks, and 8 weeks postoperatively. No recurrence was noted over a 15-month follow-up period. Histopathology of the mass indicated neurofibrosarcoma.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/11906658/