Peer-reviewed veterinary case report
Papillary renal adenoma of distal nephron differentiation in a horse.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2007
- Authors:
- Matsuda, Kazuya et al.
- Affiliation:
- Department of Veterinary Pathology · Japan
- Species:
- horse
Plain-English summary
A 20-year-old thoroughbred mare was found to have a mass in her right kidney. The mass was surrounded by a fibrous capsule and had small projections made up of a single layer of cells that looked normal under the microscope. Tests showed that these cells had certain markers similar to those found in healthy kidney tissue. Based on these findings, the mass was diagnosed as a papillary renal adenoma, which is a type of benign tumor. The treatment details and outcome were not provided in the abstract.
Abstract
A 20-year-old thoroughbred mare had a mass in the right kidney. The mass was encapsulated with fibrous capsule and composed of variably-sized papillary projections lined by a single layer of flattened to cuboidal neoplastic epithelial cells with no cytological and nuclear atypia. Immunohistochemically, the neoplastic cells were broadly positive for cytokeratin AE1/AE3 and granular staining for alpha-1-antitrypsin was focally detected; this immunohistochemical property was similar to that of the normal distal nephron. From these results, this case was diagnosed as papillary renal adenoma of distal nephron differentiation.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17675811/