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Peer-reviewed veterinary case report

Osteosarcoma of the humeral head associated with osteochondritis dissecans in a dog.

Journal:
Journal of the American Animal Hospital Association
Year:
2004
Authors:
Holmberg, Bradford J et al.
Affiliation:
College of Veterinary Medicine · United States
Species:
dog

Plain-English summary

A 6-year-old male Labrador retriever was brought to the vet because he was limping on his right front leg. This limping started five years after he had surgery for a condition called osteochondritis dissecans (OCD), which affected the same area of his shoulder. X-rays showed a large, abnormal growth in the bone, and a biopsy confirmed it was osteosarcoma, a type of bone cancer. The dog underwent surgery to remove the leg, and the examination of the tissue showed that the cancer was growing near the scar from the previous OCD surgery. This case is notable because it is the first time such a cancer has been reported in this specific area following an OCD treatment in a dog.

Abstract

A 6-year-old, male Labrador retriever was presented for lameness of the right forelimb. The lameness occurred 5 years after the dog was surgically treated for osteochondritis dissecans (OCD) of the caudal right humeral head. Radiographs revealed an expansile, osteolytic lesion occupying the entire caudal half of the right humeral head, and biopsy confirmed the diagnosis of osteosarcoma. Forelimb amputation was performed. Histopathology of the lesion and associated articular cartilage revealed neoplastic osteoblasts extensively infiltrating the marrow space adjacent to scar tissue associated with the previous OCD lesion. This is the first report of an epiphyseal osteosarcoma in the area of a previous OCD lesion in a dog.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15131107/