Peer-reviewed veterinary case report
Orbital neuroendocrine tumors in three horses.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1997
- Authors:
- Basher, A W et al.
- Affiliation:
- Department of Clinical Sciences · United States
- Species:
- horse
Plain-English summary
Three horses were seen because they had bulging eyes and other signs that suggested there was a mass in their eye socket. Two of the horses had surgery to remove the mass, while the third horse was found to have a tumor in its eye and cancer that had spread to the lungs after it passed away. Tests on the tissue showed that the masses were neuroendocrine tumors, which are rare in horses but similar to a type of tumor found in people. The two horses that had surgery were still alive 19 and 24 months later, but both experienced low blood pressure during the surgery, likely due to the tumor being handled. Overall, the treatment for the horses that had surgery was successful.
Abstract
Three horses were examined because of exophthalmos and others signs indicative of a space-occupying orbital mass. In 2 horses, exenteration was used to remove the orbital mass. In a third horse, an orbital tumor and lung metastases were found at necropsy. Routine histologic and Grimelius' histochemical staining were used on fixed tissues; immunohistochemical staining for chromogranin and electron microscopy also were performed. Masses were orbital neuroendocrine tumors. Horses that underwent exenteration were alive 19 and 24 months after surgery. Hypotension was encountered at surgery in both horses and may have been a consequence of manipulating the tumor. The orbital neuroendocrine tumors in these horses seem comparable to orbital paragangliomas found rarely in people.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/9054998/