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Peer-reviewed veterinary case report

Omental leiomyoma in a male adult horse.

Journal:
Veterinary pathology
Year:
2007
Authors:
Schaudien, D et al.
Affiliation:
Department of Pathology · Germany
Species:
horse

Plain-English summary

A large mass was found in a male adult horse during a post-mortem examination. This mass, measuring about 70 x 35 x 28 cm and weighing 41 kg, was located in the omentum major, which is a fold of tissue in the abdomen, and it wasn't connected to the digestive system. The tumor had a firm texture and was made up of several lobes that were white to yellow in color, along with some cysts filled with a fluid that looked like blood. After examining the mass under a microscope, it was determined to be an omental leiomyoma, which is a type of tumor made up of smooth muscle cells. Unfortunately, the outcome of the horse's condition is not provided in the abstract.

Abstract

A well-circumscribed mass 70 x 35 x 28 cm in size and 41 kg in weight was detected at necropsy in a male adult horse within the omentum major without any association to the gastrointestinal tract. The tumor consisted of multiple white-to-yellow lobules and displayed a firm consistency. In addition, multiple cysts filled with blood-like fluid, and multifocal areas of necrosis were observed. Histologically, the mass consisted of slightly pleomorphic spindloid-shaped cells arranged in interlacing bundles containing elongated nuclei with blunt ends. The majority of tumor cells revealed a positive immunoreaction for alpha-smooth muscle actin, vimentin, and neuron-specific enolase and were negative for S-100, factor VIII-related antigen, and glial fibrillary acidic protein. Few tumor cells showed expression of desmin and c-kit. On the basis of macroscopy, histology, and immunohistochemistry, an omental leiomyoma was diagnosed.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17846251/