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Peer-reviewed veterinary case report

Nephrotic syndrome associated with administration of sulfadimethoxine/ormetoprim in a dobermann.

Journal:
The Journal of small animal practice
Year:
2005
Authors:
Vasilopulos, R J et al.
Affiliation:
Department of Clinical Sciences · United States
Species:
dog

Abstract

This case report describes sulphonamide-induced nephrotic syndrome in a young dobermann dog. The clinical signs and laboratory abnormalities resolved shortly after discontinuation of the sulphonamide antibiotic and with generalised supportive care. Since nephrotic syndrome typically carries a guarded prognosis in veterinary medicine and is poorly responsive to therapy, a thorough drug history should be an important part of the investigation of any animal with a protein-losing nephropathy.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15909446/