Peer-reviewed veterinary case report
Nasopharyngeal conidiobolomycosis in a horse.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1996
- Authors:
- Zamos, D T et al.
- Affiliation:
- Department of Large Animal Medicine · United States
- Species:
- horse
Plain-English summary
A horse was diagnosed with a fungal infection in its throat called nasopharyngeal conidiobolomycosis, caused by a fungus known as Conidiobolus coronatus. After taking a biopsy and examining it, the horse received treatment that included an injection of a medication called amphotericin B directly into the affected area, along with sodium iodide given through an IV and potassium iodide given by mouth over two months. This treatment significantly reduced the size of the fungal growths, and follow-up endoscopy 15 months later showed that the nasal masses had completely disappeared. However, two months after that, the horse's symptoms returned, and the owner chose to euthanize the horse without further treatment. While this type of fungal infection can be treated effectively, there is a chance it can come back.
Abstract
Nasopharyngeal conidiobolomycosis caused by Conidiobolus coronatus was diagnosed in a horse after endoscopic and histopathologic examinations of a biopsy specimen. The fungal lesions in the nasopharynx were substantially reduced in size after intralesional injection of amphotericin B through the biopsy channel of a videoendoscope in combination with i.v. administration of sodium iodide and oral administration of potassium iodide during a 2-month period. Endoscopy performed 15 months after initial examination revealed regression of the granulomatous masses in the nasopharynx and complete disappearance of the nasal masses. Two months later, clinical signs recurred, and the owner elected euthanasia without evaluation and treatment. Nasopharyngeal conidiobolomycosis may be treated successfully with intralesional injection of amphotericin B in combination with administration of sodium iodide and potassium iodide, but there is a possibility of recrudescence of infection.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/8682695/